The nucleophilicity of `F^(-)` is higher in case of

Options

A. water
B. ethanol
C. DMSO
D. acetone

Answer

To determine the nucleophilicity of `F^(-)` in different solvents, we need to analyze the nature of each solvent and how it affects the nucleophilicity of fluoride ions.

### Step-by-Step Solution:

1. **Identify the Solvents**: The solvents provided are water (H2O), ethanol (C2H5OH), DMSO (Dimethyl Sulfoxide), and acetone (C3H6O).

2. **Classify the Solvents**:
- **Water (H2O)**: This is a polar protic solvent. It can form hydrogen bonds due to the presence of -OH groups.
- **Ethanol (C2H5OH)**: This is also a polar protic solvent and can form hydrogen bonds.
- **DMSO (Dimethyl Sulfoxide)**: This is a polar aprotic solvent. It does not have hydrogen atoms attached to electronegative atoms (like O or N) that can participate in hydrogen bonding.
- **Acetone (C3H6O)**: This is a polar aprotic solvent but has some ability to engage in hydrogen bonding, though less than water and ethanol.

3. **Understand Nucleophilicity**: Nucleophilicity refers to the ability of a nucleophile to donate an electron pair to an electrophile. In polar protic solvents, the presence of hydrogen bonding can hinder the nucleophilicity of anions like `F^(-)`.

4. **Evaluate the Effect of Solvent on Nucleophilicity**:
- In **polar protic solvents** (water and ethanol), hydrogen bonding stabilizes the `F^(-)` ion, reducing its nucleophilicity.
- In **polar aprotic solvents** (DMSO and acetone), there is less stabilization of the `F^(-)` ion due to the absence of hydrogen bonding, which enhances its nucleophilicity.

5. **Compare the Solvents**:
- Between DMSO and acetone, DMSO is a stronger polar aprotic solvent and provides a better environment for nucleophiles due to its ability to solvate cations without stabilizing anions as much as protic solvents do.

6. **Conclusion**: The nucleophilicity of `F^(-)` is highest in DMSO compared to the other solvents listed.

### Final Answer:
The nucleophilicity of `F^(-)` is higher in **DMSO**.