Which of the following reactions is appropriate for converting acetamide to methamine?

Options

A. Gabriels phthalimide synthesis
B. Carbylamine reaction
C. Hoffmann hypobromamide reaction
D. Stephens reaction

Answer

C

Explanation

Hoffmann bromamide reaction
`R-overset(O)overset(||)C-NH_2+Br_2+4NaOHrarrR-NH_2+Na_2CO_3+2NaBr+2H_2O`
Hoffmann developed a method for preparation of primary armies by treating an amide with bromine in an aqueous or ethanoic solution of sodium hydroxide. In this degredation reaction, migration of an alkyl or aryl group takes place from carbonyl carbon of the amide to the nitrogen atom. The amide so formed contains one carbon less than that present in the amide.