The disease caused in human due to Iodine deficiency.

Options

A. Cushing's disease
B. Cretinism
C. Insulin
D. None of these

Explanation

**Step-by-Step Solution:**

1. **Identify the Question**: The question asks for the disease caused by iodine deficiency in humans.

2. **Review the Options**: The options provided are:
- Cushing's syndrome
- Cretinism
- Insulin
- None of these

3. **Analyze Each Option**:
- **Cushing's Syndrome**: This condition is caused by the hypersecretion of adrenocorticotropic hormone (ACTH) from the pituitary gland, leading to excess cortisol production. It is not related to iodine deficiency.

- **Cretinism**: This is a condition that arises due to iodine deficiency. Iodine is essential for the production of thyroid hormones (T3 and T4). A lack of iodine leads to insufficient production of these hormones, which can cause developmental issues, particularly in children, including mental retardation and impaired physical growth.

- **Insulin**: Insulin is a hormone produced by the pancreas that regulates blood sugar levels. It is not a disease and is unrelated to iodine deficiency.

4. **Conclusion**: Based on the analysis, the disease caused by iodine deficiency is **Cretinism**.

5. **Final Answer**: The correct answer is **Cretinism**.

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