In a nucleotide the phosphate linkage is generally attached to

Options

A. C - 1 of sugar
B. C - 2 of sugar
C. C - 5 of sugar
D. N - of base

Answer

To solve the question "In a nucleotide, the phosphate linkage is generally attached to," we need to understand the structure of a nucleotide and where the phosphate group is located.

### Step-by-Step Solution:

1. **Understanding the Structure of a Nucleotide**:
A nucleotide consists of three main components: a nitrogenous base, a pentose sugar (which can be ribose or deoxyribose), and a phosphate group.

2. **Identifying the Sugar**:
The sugar in a nucleotide is a five-carbon sugar. In RNA, it is ribose, and in DNA, it is deoxyribose. The carbons in the sugar are numbered from 1' to 5'.

3. **Locating the Phosphate Group**:
The phosphate group is attached to the sugar. Specifically, it is attached to the 5' carbon of the sugar. This is a key feature of nucleotide structure.

4. **Conclusion**:
Therefore, in a nucleotide, the phosphate linkage is generally attached to the C5 of the sugar.

### Final Answer:
The phosphate linkage in a nucleotide is generally attached to C5 of the sugar.

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