Estrogen and testosterone are steroid hormones. and are most likely to bind with

Options

A. Membrane ions cannels
B. Enzyme-linked membrane receptors
C. G - protein linked membrane
D. Cytoplasmic receptors

Answer

To solve the question regarding where estrogen and testosterone, which are steroid hormones, are most likely to bind, we can follow these steps:

### Step-by-Step Solution:

1. **Identify the Nature of Steroid Hormones**:
- Estrogen and testosterone are classified as steroid hormones. Steroid hormones are lipid-soluble due to their chemical structure.

**Hint**: Remember that steroid hormones are derived from cholesterol and are hydrophobic.

2. **Understand Hormone Receptor Interaction**:
- Steroid hormones can pass through the cell membrane because they are lipid-soluble. This allows them to interact with receptors that are not only on the cell membrane but also inside the cell.

**Hint**: Consider how the lipid solubility of these hormones affects their ability to cross cell membranes.

3. **Identify Possible Receptor Locations**:
- The receptors for steroid hormones can be found in three main locations:
- Plasma membrane
- Cytosol (the fluid inside the cell)
- Nucleus (the control center of the cell)

**Hint**: Think about where receptors for lipid-soluble substances are typically located.

4. **Determine the Most Likely Binding Site**:
- Given that steroid hormones can easily pass through the plasma membrane, they are most likely to bind to receptors located in the cytosol or the nucleus rather than on the plasma membrane itself.

**Hint**: Recall that steroid hormones often exert their effects by altering gene expression, which typically involves binding to intracellular receptors.

5. **Conclude the Answer**:
- Since estrogen and testosterone primarily bind to receptors that are located inside the cell (cytosol or nucleus), the most appropriate answer is that they bind with cytoplasmic receptors.

**Final Answer**: The correct answer is **Cytoplasmic Receptors**.

### Summary:
Estrogen and testosterone, being steroid hormones, are most likely to bind with cytoplasmic receptors due to their lipid-soluble nature, allowing them to pass through the cell membrane and interact with intracellular receptors.