Assertion : With in the mitochondrion, the proton grandient develops across the inter membrane space.
Reason : The place in mitochondrion where pH is lowest is inter membrance space.

Options

A. If both Assertion and Reason are true and Reason is correct explanation of Assertion.
B. If both Assertion and Reason are true but Reason is not a correct explanation of Assertion.
C. If Assertion is true but Reason is false.
D. If both Assertion and Reason are false.

Answer

To analyze the given question, we will break it down into the Assertion and Reason statements and evaluate their truthfulness and relationship.

### Step 1: Understanding the Assertion
The assertion states: "Within the mitochondrion, the proton gradient develops across the intermembrane space."

- In mitochondria, during cellular respiration, protons (H⁺ ions) are pumped from the mitochondrial matrix into the intermembrane space. This creates a higher concentration of protons in the intermembrane space compared to the matrix, establishing a proton gradient.
- Therefore, the assertion is **True**.

### Step 2: Understanding the Reason
The reason states: "The place in mitochondrion where pH is lowest is the intermembrane space."

- The pH in the intermembrane space is affected by the concentration of protons. When protons are pumped into the intermembrane space, the pH decreases, indicating higher acidity. However, the pH in the intermembrane space is approximately neutral (around 7.0) under normal conditions, not the lowest.
- Therefore, the reason is **False**.

### Step 3: Evaluating the Relationship
Now we need to determine if the reason correctly explains the assertion.

- Since the assertion is true and the reason is false, the reason does not provide a correct explanation for the assertion.

### Conclusion
Based on the evaluation:
- **Assertion**: True
- **Reason**: False
- The correct answer is that the assertion is true, and the reason is false.

### Final Answer
The appropriate option is: **Assertion is true and Reason is false.**

---