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Write a note on S(N)2 mechanism....

Write a note on `S_(N)2` mechanism.

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The reaction in which the reaction rate depends both on the concentration of substrate and nucleophile is called `S_(N)2` reaction or substitution nucleophilic biomolecular reactions. For example, reaction between `CH_(3)-Cl` and hydroxide ion to yield methanol and chloride ion follows a second order kinetics.

The incoming nucleophile interacts with the alkyl halide causing the carbon - halide bond to break and a new bond is formed between carbon and attacking nucleophile. Here it is C - O bond formed between C and - OH. These two processes take place simultaneously in a single step and no intermediate is formed.
In a reaction, the bond between incoming nucleophile and the carbon atom starts forming, the bond between carbon atom and leaving group weakens and as a result, the carbon - hydrogen bonds of the substrate start moving away from the nuclephile. In a transition state all the three C - H bonds are in the same plane and the attacking and leaving nucleophiles are partially attached to the carbon. Thus, in a transition state carbon is bonded to five atoms simultaneoulsy. Such structure is unstable and cannot be isolated.
During the reaction, as the attacking nucleophile approaches closer to the carbon, C - H bonds still keep on moving in the same direction till attacking nucleophile attaches the carbon and leaving group leaves the carbon. This is known as inverted in a same way as an umbrella is inerted in a same way as umbrella is inverted inside out when caught in a strong wind.
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KUMAR PRAKASHAN-HALOALKANES AND HALOARENES-SECTION - A QUESTIONS
  1. Write a note on nucleophillc substitution reactions.

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  2. Write a note on nucleophiles.

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  3. Write a note on S(N)2 mechanism.

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  4. Explain the factors favouring S(N)2 reaction.

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  5. Write a note on S(N)1 reaction.

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  6. Explain the factors affecting S(N)1 reaction.

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  7. Enlist the main points of difference between S(N)1 and S(N)2 reactions...

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  8. What is retention and inversion of configuration ? Explain with suitab...

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  9. Explain stereochemistry of S(N)1 reaction with suitable example.

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  10. Explain stereochemistry of S(N)2 reaction with suitable example.

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  11. Explain Elimination reactions of alkyl halides.

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  12. Explain dehydrohalogenation (beta - elimination) of alkyl halides.

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  13. Explain how sustitution and elimination reactions compete in the same ...

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  14. Write a note on Grignard Reagent.

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  15. Write a note on Wurtz Reaction.

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  16. Explain why aryl halides are extermely less reactive towards nucleophi...

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  17. Give the reaction of hydroxyl group with chlorobenzene.

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  18. Explain why the electron withdrawing groups such as -NO(2) show its ef...

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  19. Why aryl halides undergo electrophilic substitution reactions at o - a...

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  20. Give following reaction of aryl halides : (i) Halogenation (ii...

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