Adjacent epithelial cells are held together by desmosomes.

Answer

### Step-by-Step Solution:

1. **Understanding the Question**: The question states that adjacent epithelial cells are held together by desmosomes. We need to determine if this statement is true or false.

2. **Definition of Desmosomes**: Desmosomes, also known as macula adherens, are specialized structures that facilitate cell-to-cell adhesion. They play a crucial role in maintaining the integrity of tissues by holding adjacent cells together.

3. **Function of Desmosomes**: Desmosomes help resist mechanical stress and shear forces between cells. This is particularly important in tissues that experience significant stretching or movement, such as epithelial and cardiac tissues.

4. **Location of Desmosomes**: Desmosomes are commonly found in stratified squamous epithelium, which is a type of epithelial tissue that provides protection against abrasion and is found in areas like the skin and lining of the mouth.

5. **Conclusion**: Since desmosomes are indeed responsible for holding adjacent epithelial cells together, the statement in the question is true.

### Final Answer: True

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