Why does respiration considered as an exothermic reaction ? Explain.

Explanation

Respiration involves the breakdown of substrates so traditionally called catabolic process and the respiratory pathway sas a catabolic pathway. In respiration, different substrates enter into respiratory pathway at different points. If fatty acids were respired, they would be degraded to acetyl CoA and enter the pathway. Glycerol would enter the pathway after converted to PGAL. The proteins and the aminoacids would enter the pathway at pyruvate.
Fatty acids would be brokendown to acetyl CoA before entering into respiratory pathway. But when the organism needs to synthesis fatty acids, Acetyl CoA would be withdrawn from the respiratory pathway for it. Hence the respiratory pathway comes into the picture both during the breakdown and the synthesis of fatty acids. In this issue, respiratory pathway is involved in both anabolism and catabolism, it would be better to consider it as amphibolic pathway rather than as a catabolic one.