During an enzyme catalyze reaction , the substrate reaches a transition stage Which is

Options

A. Temporary but stable
B. Permanent but unstable
C. Temporary and unstable
D. Permanent and stable

Answer

**Step-by-Step Solution:**

1. **Understanding Enzyme-Catalyzed Reactions**: Enzymes are biological catalysts that speed up chemical reactions by lowering the activation energy required for the reaction to occur.

2. **Substrate and Transition State**: In an enzyme-catalyzed reaction, the substrate (the molecule upon which the enzyme acts) binds to the enzyme's active site, forming an enzyme-substrate complex.

3. **Formation of the Transition State**: As the substrate binds to the enzyme, it undergoes a transformation into a transition state. This transition state is a temporary and unstable configuration that represents a point of maximum energy along the reaction pathway.

4. **Characteristics of the Transition State**: The transition state is characterized by:
- **High Reactivity**: The bonds in the substrate are in the process of being broken and formed, making the transition state highly reactive.
- **Unstable Nature**: It is not a stable state; it exists only for a very short period before converting into the product.

5. **Conversion to Product**: After reaching the transition state, the enzyme catalyzes the conversion of the substrate into the product, which is then released from the enzyme, allowing the enzyme to catalyze further reactions.

6. **Conclusion**: Therefore, during an enzyme-catalyzed reaction, the substrate reaches a transition state that is temporary and unstable.

**Final Answer**: The transition state during an enzyme-catalyzed reaction is temporary and unstable.

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