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What is the Zwitterion?...

What is the Zwitterion?

A

The carboxyl group can lose a proton and amino group can accept a proton in the aqueous solution with give rise to a dipolar ion

B

The carboxyl group can accept a proton and amino group can lose a proton in aqueous solution which give rise to a dipolar ion

C

The amino group can accept a proton and ester group can lose a proton in aqueous solution which give rise to dipolar ion

D

Thy amino group can lose a proton in aqueous solution and ester group can accept a proton in aqueous solution which give rise to the dipolar ion

Text Solution

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### Step-by-Step Solution 1. **Definition of Zwitterion**: A zwitterion is a molecule that has both positive and negative charges but is overall electrically neutral. This typically occurs in amino acids, which contain both an amino group (-NH2) and a carboxyl group (-COOH). 2. **Formation of Zwitterion**: In an aqueous solution, the carboxyl group can lose a proton (H⁺), resulting in a negatively charged carboxylate ion (-COO⁻). Simultaneously, the amino group can accept a proton, resulting in a positively charged ammonium ion (-NH3⁺). 3. **Charge Distribution**: The presence of both these charged groups in the same molecule leads to a dipolar ion, which is characteristic of zwitterions. The molecule has a positive charge on one part (the ammonium ion) and a negative charge on another part (the carboxylate ion), but the overall charge of the molecule is neutral. 4. **Example in Amino Acids**: Most amino acids exist as zwitterions at physiological pH (around 7.4). For example, in the case of glycine (the simplest amino acid), it can be represented as: - At low pH: NH3⁺ - CH2 - COOH (protonated amino group, protonated carboxyl) - At neutral pH: NH3⁺ - CH2 - COO⁻ (protonated amino group, deprotonated carboxyl) - At high pH: NH2 - CH2 - COO⁻ (deprotonated amino group, deprotonated carboxyl) 5. **Conclusion**: Thus, a zwitterion is specifically formed when the carboxyl group of an amino acid loses a proton and the amino group accepts a proton, resulting in a molecule that has both a positive and a negative charge.
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Knowledge Check

  • Which of the above is Zwitterionic form?

    A
    A
    B
    C
    C
    B
    D
    All
  • Assertion : The K_(a) value of alpha -amino acids is very low. Reason : alpha -Amino acids have zwitterionic structure.

    A
    If both assertion and reason are correct and reason is correct explanation for assertion.
    B
    If both assertion and reason are correct but reason is not correct explanation for assertion.
    C
    If assertion is correct but reason is incorrect.
    D
    If assertion and reason are both incorrect.
  • Statement :1 The K_a values of alpha -amino acids are very low. Statement- 2: alpha -amino acids have zwitterionic structures.

    A
    Statement -1 is True , Statement -2 is True, Statement -2 is a correct explanation of Statement -1
    B
    Statement -1 is True , Statement -2 is True, Statement -2 is not a correct explanation for Statement -1
    C
    Statement -1 is True , Statement -2 is False
    D
    Statement -1 is False, Statement -2 is True.
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