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STATEMENT-1 : Primary structure of prote...

STATEMENT-1 : Primary structure of proteins is determined by amino acid sequence.
and
STATEMENT-2 Intramolecular hydrogen bonding between carbonyl group and `-overset(|)N-H` group is responsible for the folding of polypeptide chain.

A

Statement-1 is True, Statement-2 is True, Statement-2 is a correct explanation for Statement-1

B

Statement-1 is True, Statement-2 is True, Statement-2 is NOT a corrèct explanation for Statement-1

C

Statement-1 is True, Statement-2 is False

D

Statement-1 is False, Statement-2 is True

Text Solution

AI Generated Solution

The correct Answer is:
To analyze the statements provided in the question, we will evaluate each statement separately and then determine their relationship. ### Step 1: Evaluate Statement 1 **Statement 1:** "Primary structure of proteins is determined by amino acid sequence." - The primary structure of a protein refers to the linear sequence of amino acids that make up the polypeptide chain. - Each protein has a unique sequence of amino acids, which is dictated by the genetic code. - Therefore, this statement is **true**. ### Step 2: Evaluate Statement 2 **Statement 2:** "Intramolecular hydrogen bonding between carbonyl group and `-NH` group is responsible for the folding of polypeptide chain." - Intramolecular hydrogen bonding occurs when a hydrogen atom covalently bonded to a more electronegative atom (like nitrogen in the `-NH` group) is attracted to another electronegative atom (like oxygen in the carbonyl group). - This type of bonding is crucial for stabilizing the secondary structure of proteins, such as alpha-helices and beta-sheets. - Therefore, this statement is also **true**. ### Step 3: Determine the Relationship Between the Statements - While both statements are true, they address different aspects of protein structure. - Statement 1 discusses the primary structure (amino acid sequence), while Statement 2 discusses the folding of the polypeptide chain, which is related to secondary, tertiary, and quaternary structures. - There is no direct relationship between the two statements, as one does not imply or depend on the other. ### Conclusion Both statements are true, but they are independent of each other. ### Final Answer Both statements are true, but there is no relationship between them. ---
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Knowledge Check

  • Statement-1 : Boiling point of H_(2)O is more than HF . and Statement-2 : Intermolecular hydrogen bonding in HF is stronger than H_(2)O .

    A
    H - F has highest van der Waals forces and dipole moment.
    B
    H - F has highest London forces.
    C
    H - F has highest dipole moment hence has dipole - dipole , London forces and hydrogen bonding.
    D
    H - F has strong intermolecular interactions like dipole - induced dipole.

  • During chain elongation, peptide bond is formed between carboxyl group of first and amino group of second amino acid by

    A
    Peptidyl transferase
    B
    Taq polymerase
    C
    DNA ligase
    D
    Helicase