Oxygen haemoglobin dissociation curve will shift to right on decrease of

Options

A. Acidity
B. Carbon dioxide concentration
C. Temperature
D. pH

Answer

To answer the question regarding the factors that cause the oxygen-hemoglobin dissociation curve to shift to the right, we can follow these steps:

### Step-by-Step Solution:

1. **Understanding the Oxygen-Hemoglobin Dissociation Curve**:
- The oxygen-hemoglobin dissociation curve is a graphical representation that shows how readily hemoglobin binds to oxygen at different partial pressures of oxygen. It typically has a sigmoid shape.

2. **Identifying the Shift**:
- The curve can shift to the left or right. A rightward shift indicates that hemoglobin is releasing oxygen more readily, which is often referred to as a decrease in hemoglobin's affinity for oxygen.

3. **Factors Influencing the Shift**:
- The right shift can be influenced by several factors, including:
- Increased carbon dioxide concentration (or partial pressure of CO2)
- Increased temperature
- Decreased pH (increased acidity)
- Increased levels of 2,3-bisphosphoglycerate (2,3-BPG)

4. **Analyzing the Options**:
- Given the options: acidity, carbon dioxide concentration, temperature, or pH, we need to determine which factor, when decreased, would cause a right shift.
- A decrease in pH (which means an increase in acidity) leads to a rightward shift in the curve. Conversely, if pH increases (decreases acidity), the curve shifts to the left.

5. **Conclusion**:
- Therefore, the oxygen-hemoglobin dissociation curve will shift to the right when there is a decrease in pH (which corresponds to an increase in acidity).

### Final Answer:
The oxygen-hemoglobin dissociation curve will shift to the right on a decrease of **pH** (increased acidity).