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Assertion :- In the tissue high P(CO(2))...

Assertion `:-` In the tissue high `P_(CO_(2))`, low `P_(O_(2))` , higher `H^(o+)` concentration conditions are favourable for dissociation of oxygen from the oxyhaemoglobin.
Reason `:-` Every 100ml of oxygenated blood can deliver around 5ml of `O_(2)` to the tissues under normal physiological conditions.

A

If both Assertion & Reason are True & the Reasonn is a correct explanation of the Assertion .

B

If both Assertion & Reason are True but Reason is not a correct explanation of the Assertion

C

If Assertion is True but the Reason is False.

D

If both Assertion & Reason are false.

Text Solution

AI Generated Solution

The correct Answer is:
To solve the assertion and reason question, we will analyze each part step by step. ### Step 1: Understand the Assertion The assertion states that in tissues with high \( P_{CO_2} \), low \( P_{O_2} \), and higher \( H^+ \) concentration, conditions are favorable for the dissociation of oxygen from oxyhemoglobin. - **High \( P_{CO_2} \)**: When carbon dioxide levels are high, it indicates that tissues are metabolically active and consuming oxygen. - **Low \( P_{O_2} \)**: A low partial pressure of oxygen means that oxygen is being used up by the tissues, creating a gradient that favors oxygen release from hemoglobin. - **Higher \( H^+ \) concentration**: Increased \( H^+ \) concentration (lower pH) occurs due to the conversion of \( CO_2 \) to bicarbonate and protons in the blood. This acidic environment promotes the Bohr effect, which enhances oxygen release from hemoglobin. **Conclusion**: The assertion is true. ### Step 2: Understand the Reason The reason states that every 100 ml of oxygenated blood can deliver around 5 ml of \( O_2 \) to the tissues under normal physiological conditions. - This refers to the oxygen-carrying capacity of blood. Under normal conditions, the blood can indeed deliver approximately 5 ml of oxygen per 100 ml of blood to the tissues. This is a standard physiological fact. **Conclusion**: The reason is also true. ### Step 3: Determine the Relationship Now we need to evaluate whether the reason is the correct explanation of the assertion. - The assertion discusses the conditions that favor the dissociation of oxygen from hemoglobin, while the reason provides a fact about the amount of oxygen delivered by blood. - Although both statements are true, the reason does not explain why the conditions mentioned in the assertion favor oxygen dissociation. **Conclusion**: The reason is not the correct explanation of the assertion. ### Final Answer Both the assertion and the reason are true, but the reason is not the correct explanation of the assertion. Therefore, the correct option is: **Option B**: Assertion and reason are true, but reason is not the correct explanation of assertion. ---
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Knowledge Check

  • Assertion : A sigmoid curve is obtained when percentage saturation of haemoglobin with O_(2) is plotted against the PO_(2) . Reason : Every 100 mL of oxygenated blood can deliver around 5mL of O_(2) to the tissues under normal physiological conditions.

    A
    If both assertion and reason are true and reason is the correct explanation of assertion
    B
    If both assertion and reason are true and reason is not the correct explanation of assertion
    C
    If assertion is true but reason is false.
    D
    If both assertion and reason are false.

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