The interstitial cells of the testes synthesize and secrete:

Options

A. Androgens
B. Luteinizing hormone
C. Aldosterone
D. Interstitial cell-stimulating hormone

Answer

To solve the question regarding what the interstitial cells of the testes synthesize and secrete, we can follow these steps:

### Step-by-Step Solution:

1. **Identify the Location of Interstitial Cells**:
- Interstitial cells, also known as Leydig cells, are located in the interstitial space outside the seminiferous tubules of the testes.

2. **Understand the Function of Interstitial Cells**:
- These cells are part of the endocrine system and are responsible for the synthesis and secretion of hormones.

3. **Determine the Type of Hormones Produced**:
- The primary hormones produced by interstitial cells are known as androgens, which are male sex hormones.

4. **Evaluate the Options Given**:
- Option 1: Androgens - This is the correct answer as interstitial cells secrete androgens.
- Option 2: Luteinizing hormone - This hormone is produced by the pituitary gland, not the interstitial cells.
- Option 3: Aldosterone - This hormone is produced by the adrenal glands, not the interstitial cells.
- Option 4: Interstitial cell-stimulating hormone - This is not a hormone secreted by interstitial cells; rather, it stimulates them.

5. **Conclusion**:
- Based on the above analysis, the interstitial cells of the testes synthesize and secrete androgens.

### Final Answer:
The interstitial cells of the testes synthesize and secrete **androgens** (Option 1).