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The pK(a) of acteylsalicylic acid (aspir...

The `pK_(a)` of acteylsalicylic acid (aspirin) is `3.5`. The pH of gastric juice in human stomach is about `2-3` and the pH in the small intestine is about 8. Aspirin will be:

A

Unionised in the small intestine and in the stomach .

B

Completely ionised in the small intestine and in the stomach.

C

Ionised in the stomach and almost unionised in the small intestine.

D

Ionised in the small intestine and almost unionised in the equilibrium

Text Solution

Verified by Experts

The correct Answer is:
D
(d) Gastric juice is acidic . Hence the ionisation of aspirin is suppressed whereas small intestine has basic medium. Therefore aspirin is more ionised here.
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