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The reaction between carbonyl compound a...

The reaction between carbonyl compound and `alpha`-bromoesters in the presence of metal Zn to give `beta`-hydroxy ester is known as:

A

Clemmensen reduction

B

Reformatsky reaction

C

Wolff-Kishner reaction

D

Grignard reaction

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The correct Answer is:
To solve the question regarding the reaction between carbonyl compounds and alpha-bromoesters in the presence of zinc, leading to the formation of beta-hydroxy esters, we can follow these steps: ### Step-by-Step Solution: 1. **Identify the Reactants**: - The reactants in the reaction are a carbonyl compound (which can be an aldehyde or a ketone) and an alpha-bromoester. 2. **Understand the Role of Zinc**: - Zinc acts as a reducing agent in this reaction. It interacts with the halide (bromine in this case) of the alpha-bromoester, facilitating the formation of a carbanion. 3. **Formation of Carbanion**: - The zinc reacts with the alpha-bromoester, leading to the formation of a carbanion. This carbanion is nucleophilic and can attack the electrophilic carbonyl carbon of the carbonyl compound. 4. **Nucleophilic Attack**: - The carbanion generated from the alpha-bromoester attacks the carbonyl carbon, resulting in the formation of a beta-hydroxy ester. This step involves the breaking of the carbonyl double bond and the formation of a new bond between the carbanion and the carbonyl carbon. 5. **Protonation**: - After the nucleophilic attack, the intermediate formed can be protonated (typically by adding an acid) to yield the final product, which is a beta-hydroxy ester. 6. **Identify the Reaction Type**: - The overall reaction can be classified as a nucleophilic substitution reaction, specifically a reaction known as the "Deformity reaction" or "Deformity reaction" (often referred to as the "De Forn-Midsy reaction"). This reaction is characterized by the formation of beta-hydroxy esters from carbonyl compounds and alpha-bromoesters in the presence of zinc. ### Final Answer: The reaction between carbonyl compounds and alpha-bromoesters in the presence of zinc to give beta-hydroxy esters is known as the **De Forn-Midsy reaction**.
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