Connecting link between glycolysis and TCA cycle is

Explanation

The connecting link between glycolysis and TCA cycle is the link reaction or acetylation of pyruvate .
Pyruvic acid undergoes oxidative decarboxylation before entering Kreb's cycle . Removal of carbon dioxide along with oxidation by removal of `2H^(+)` takess palce. The reaction is catalyzed by enzyme pyruvic dehydrogenase ( oxidase). Co-enzyme NAD and coenzyme - A , are required for this reaction . Pyruvic acid (3C) underfoes decarboxylation first and then oxidation by removal of `2H^(+)`, which is taken up by NAD and `NADH_(2)` is formed . Acetyl fraction (2C) that remains after decarboxylation is taken up by coenzyme A and Acetyl Co-A is formed . This is called Acetylation of Pyruvate .
Glycolysis ends with the formation of pyruvate and after acetylation enters as acetyl Co-A in the kreb's cycle . Pyruvate is converted to acetyl co - enzyme -A in the mitochondrial matrix . The whole process can be represented as follows .