The binding of oxygen by haemoglobin (Hb) giving oxy-haemoglobin `(HbO_(2))`, is partially regulated by the concentration of `H_(3)O^(+)` and dissolved `CO_(2)` in blood
`HbO_(2)+H_(2)O^(+)+CO_(2)hArr H^(+)Hb-CO_(2)+O_(2)+H_(2)O` If there is production of lactive acid and `CO_(2)` in a muscle during exertion, then `:`