The inhibitor which does not resemble the substrate in structure and binds to the enzyme at site other than the active site is called

Options

A. competitive inhibitor
B. non-competitive inhibitor
C. activator
D. substrate analogue.

Answer

B

Explanation

In non-competitve inhibition, the inhibitor binds at a site other than the active site ob the enzyme surface. This binding impairs the enzyme function. The inhibitor has no structural resemblance with the sunstrate. It does not interfere with the enzyme-substrate binding but the catalysis is prevented, possibly due to a distortion in the enzyme conformation. Non-competitive inhibition is usually irreversible because it cannot be overcome by increasing the substrate concentration. The inhibitor (l) generally binds with the enzyme as well as the ES complex. The overall relation in non.competitve inhibition is represented as :