Holoenzyme is the complete enzyme consisting of an apoenzyme and a co-factor. Select the option that correctly identifies the nature of apoenzyme and co-factor.

Options

A. `{:("Apoenzyme","Co-factor"),("Protein" ,"Non-protein"):}`
B. `{:("Apoenzyme","Co-factor"),("Non-protein" ,"Protein"):}`
C. `{:("Apoenzyme","Co-factor"),("Protein" ,"Protein"):}`
D. `{:("Apoenzyme","Co-factor"),("Non-protein" ,"Non-protein"):}`

Answer

A

Explanation

Enzyme may be broadly classified into two types depending on their chemical composition-simple enzymes and conjugated enzymes are wholly made up of proteins and any additional substance or group is absent, e.g., pepsin, trypsin, etc. Conjugated enzymes (or holoenzymes) are formed of two parts -a protein part called apoenzyme and a non-protein part named co-factor. The complete conjugated enzyme consisting of an apoenzyme and a co-factor is called holoenzyme. Holoenzyme is the functional unit of enzyme.
`underset(("Active enzyme"))("Holoenzyme")rarr underset(("Protein part"))("Apoenzyme")+underset(("Non-protein part"))("Co-factor")`
Co-factor may be inorgainc or roganic in nature. Catalytic activity is lost when co-factor is removed from the enzyme which indicates that it plays a crucial role in catalytic activity of enzymes.