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Assertion: Reductive amination involves ...

Assertion: Reductive amination involves the transfer of amino group from one amino acid to the keto group of a keto acid.
Reason: In reductive amination, transfer of `NH_(2)` from glutamic acid takes place.

A

If both assertio and reason are true and reason is the correct explanation of assertion

B

if both assertion and reason are true but reason is not the correct explanation of assertion

C

if assertion is true but reason is false

D

if both assertion and reason are false

Text Solution

Verified by Experts

The correct Answer is:
D

In reductive amination in the presence of enzyme glutamate dehydrogenase and a reduced coenzyme (NADH or NADPH), ammonia can directely combine with `alpha`-ketoglutaric acid to from a an amino acid. On the other hand, transamination is transfer of amino group `(-NH_(2))` of one amino acid with the keto group (gt C=O) of keto acid. in transaminase, transfer of `NH_(2)` from glutamic acid takes place. The enzyme required is transaminase or aminostransferase.
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