State the role of pancreatic juice in digestion of proteins.

Explanation

Pancreatic juice contains a variety of inactive enzymes such as trypsinogen, chymotrypsinogen, and carboxypeptidases. These enzymes play an important role in the digestion of proteins. Physiology of protein-digestion The enzyme enterokinase is secreted by the intestinal mucosa. It activates trypsinogen into trypsin.
`"Trypsinogen" overset ("Enterokinase")rarr|"Trypsin + Inactive peptide "`
Trypsin then activates the other enzymes of pancreatic juice such as chymotrypsinogen and carboxypeptidase. Chymotrypsinogen is a milk-coagulating enzyme that converts proteins into peptides.
`underset("(Inactive)")"Chymotrypsinogen" overset("Trypsin")rarr underset("(Active)")"Chymotrypsin "`
`"Proteins" overset("Chymotrypsin")rarr"Peptides "`
Carboxypeptidase acts on the carboxyl end of the peptide chain and helps release the last amino acids. Hence, it helps in the digestion of proteins.
`"Peptides" overset("Carboxypeptidase")rarr"Smaller peptide chain + Amino acids"`
Thus, in short, we can say that the partially-hydrolysed proteins present in the chyme are acted upon by various proteolytic enzymes of the pancreatic juice for their complete digestion.
`"Proteins, peptones"overset("Trypsin/Chymotrypsin")underset("Carboxypeptidase")rarr "Dipeptides and proteases"`