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The number of disulphide linkage present...

The number of disulphide linkage present in insulin are

A

3

B

4

C

1

D

2

Text Solution

Verified by Experts

The correct Answer is:
D
Human insulin (mol wt. 5,734) contains 51 amino acids, arranged in two polypeptide chains. The chain A has 21 amino acids while B has 30 amino acid. Both are held together by two interchain disulphide bridges, connecting `A_(7)` to `B_(7)` and `A_(20)` to `B_(19)`. in addition there is an intrachain disulphide linkage in case of proinsulin.
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