Which of the following statements are correct with reference to isoelectric point?

Options

A. The isoelectric point is the pH at which the amino acid bears no net charge
B. It corresponds to pH at which the concentration of the zwitter ion is at a maximum
C. It is not the average of `pK_(a_(1))` and `pK_(a_(2))` values
D. All of these

Answer

A, B

Explanation

At the isoelectric point, the amino acids exist as zwitter ion to the maximum ion concentration
A zwitter ion is dipolar ion , i.e, `R-underset(o+)underset(NH_(3)underset(|)(CH)-COO^(Theta)` The net charge is zero
Hence choices (a) and (b) are correct while (c) and (d) are incorrect.