The first 5C dicarboxylic acid in Krebs' cycle whic is used in nitrogen metabolism is

Options

A. OA A
B. citric acid
C. `alpha`-ketoglutaric acid
D. acetyl coenzyme A

Answer

C

Explanation

The first 5 carbon dicarboxylic acid in Krebs' cycle is `alpha`- ketoglutaric acid. The `alpha-` ketoglutrate that accumulatews when `alpha`-ketoglutarate dehydrogenase is inhibited can be used in nitrogen metabolism as a precursor for serveral amino acids and the purine bases
`alpha-` ketoglutrate `rarr` Glutamate `rarr` Other amino acids `rarr` Purines
`alpha`- ketoglutarate of Kreb's cycle produces an important amino acid called glutamate on amination.