Study the following statements regarding chemiosmotic hypothesis in mitochondria and select the correct ones.
(i) `F_(1)` headpiece contains the site for the synthesis of ATP from `ADP + Pi`.
(ii) `F_(0)` par forms the channel through which protons cross the inner membrane.
(iii) For each ATP produced, `2H^(+)` pass through `F_(0)` from the intermembrane space to the matrix down the electrochemical proton gradient.

Options

A. (i) and (ii)
B. (ii) and (iii)
C. (i) and (iii)
D. (i),(ii) and (iii)

Answer

To solve the question regarding the chemiosmotic hypothesis in mitochondria, we need to analyze each statement provided and determine whether they are correct or not.

### Step-by-Step Solution:

1. **Statement (i):** `F_(1)` headpiece contains the site for the synthesis of ATP from `ADP + Pi`.
- The F1 headpiece is indeed where ATP synthesis occurs. It contains the enzyme ATP synthase, which catalyzes the formation of ATP from ADP and inorganic phosphate (Pi).
- **Conclusion:** This statement is **correct**.

2. **Statement (ii):** `F_(0)` part forms the channel through which protons cross the inner membrane.
- The F0 part of the ATP synthase complex acts as a channel that allows protons (H⁺ ions) to flow across the inner mitochondrial membrane. This flow of protons is crucial for ATP synthesis as it drives the rotation of the F1 part.
- **Conclusion:** This statement is **correct**.

3. **Statement (iii):** For each ATP produced, `2H^(+)` pass through `F_(0)` from the intermembrane space to the matrix down the electrochemical proton gradient.
- Initially, it was thought that 2 protons were required to produce one ATP. However, more recent findings indicate that approximately 3.3 protons are needed for the synthesis of one ATP molecule. Therefore, the statement that only 2 protons are required is outdated.
- **Conclusion:** This statement is **incorrect**.

### Final Evaluation:
- Statement (i) is correct.
- Statement (ii) is correct.
- Statement (iii) is incorrect.

Thus, the correct statements regarding the chemiosmotic hypothesis are (i) and (ii).

### Correct Answer:
The correct options are (i) and (ii).