Refer to the given graph representing interplay of different hormones (A-D) during menstrual cycle in women and answer the question that follow.

Cessation of secretion of which of these hormones may lead to osteoporosis?

Options

A. A
B. B
C. C
D. D

Answer

A

Explanation

A represents hormone estrogen. In old age, after menopause, almost no estrogens are secreted by the ovaries. This estrogen deficiency leads to (1) increased osteoclastic activity in the bories, (2) decreased bone matrix, and (3) decreased deposition of bone calcium and phosphate. In some women, this effect is extremely severe, and the resulting condition is osteoporosis.