During anaphase -I of meiosis

Options

A. Homologous chromosomes separate
B. Non-homologous autosomes separate
C. Sister chromatids separate
D. Non-sister chromatids separate

Answer

**Step-by-Step Solution:**

1. **Understanding Anaphase I of Meiosis:**
Anaphase I is a crucial stage in meiosis, which is the process of cell division that reduces the chromosome number by half and leads to the formation of gametes. During this phase, homologous chromosomes are separated and pulled toward opposite poles of the cell.

2. **Separation of Homologous Chromosomes:**
In Anaphase I, the pairs of homologous chromosomes, which were aligned at the metaphase plate during Metaphase I, are separated. Each chromosome of the homologous pair is pulled to opposite ends of the cell by the spindle fibers.

3. **Role of Spindle Fibers:**
The spindle fibers, which are formed from the centrioles, play a crucial role in this separation. They attach to the centromeres of the homologous chromosomes and help in their movement toward the poles.

4. **Formation of Daughter Cells:**
As the homologous chromosomes are pulled apart, the cell prepares to divide. At the end of Anaphase I, each pole of the cell will have a complete set of chromosomes, but each set will only contain one chromosome from each homologous pair.

5. **End of Meiosis I:**
After Anaphase I, the cell will proceed to Telophase I, where the chromosomes will de-condense, and the cell will divide into two daughter cells, each with half the original number of chromosomes.