Alteration of which genes leads to cancer

Options

A. Cell proliferation gene (proto-oncogenes)
B. Tumor suppressor gene
C. Tumor virus gene
D. All of these

Answer

A

Explanation

(a) In human being cancer is caused by extra-activation of certain genes called proto-oncogenes into cellular oncogenes. Proto- oncogenes typically encode proteins receptors, signal transduction proteins, and transcription factors. Multation in these genes tend to relax control mechanisms and accelerate cell division, leading to cell proliferation that is characteristic of cancer. Tumor suppressor gene normally keeps mitosis in check & prevent cancer from occuring.