Explain end product inhibition or negative feedback inhibition.

Explanation

1. When the end product of a metabolic pathway begins to accumulate, it may act as an allostenc inhibitor of the enzyme controlling the first step of the pathway.
2. Thus the product starts to switch off its own production as it bmlds up. The process is self - regulatory. As the product is used up, its production is switched back on again. This is called end-product inhibition.