What is the effect of denaturation on the structure of proteins?

Explanation

During denaturation, `2^(@)` and `3^(@)` structure of proteins are destroyed but `1^(@)` structure remains intact. As a result of denaturation, die globular proteins (soluble in `H_(2)O`) are converted into fibrous proteins (insoluble in `H_(2)O`) and their biological activity is lost. For example, boiled egg which contains coagulated proteins cannot be hatched.