Identify the wrong combination related to Chromosomal disorders (A) Failure of segregation of chromatids - aneuploidy (B) Patau's syndrome - severe intellectual disability and physical abnormalities (C) Broad shield like chest with widely spaced nipples - Turner's syndrome (D) Klinefelter's male - negative for Barr body

Chromosomal disorders are caused due to absence or excess or abnormal arrangement of one or more chromosomes. Failure of segregation of chromatids during cell division cycle results in the gain or loss of a chromosome, and is called aneuploidy. Failure of cytokinesis after telophase stage of cell division results in an increase in a whole set of chromosomes in an organism and, this is known as polyploidy. Turner's syndrome is caused due to ............... of one of the X chromosome.