Which of the following are mitotic poisons :-

Options

A. Colchicine
B. Mustard gas and Azides
C. Cyanides
D. All of these

Answer

To determine which of the following are mitotic poisons, we need to understand what mitotic poisons are and evaluate each option provided.

### Step-by-Step Solution:

1. **Understanding Mitotic Poisons**:
- Mitotic poisons are chemical compounds that interfere with cell division. They can disrupt the formation of the spindle apparatus or affect the DNA damage checkpoints, leading to cell death (apoptosis).

2. **Evaluating the Options**:
- **Option 1: Causasein**:
- Causasein is known to inhibit the formation of the spindle apparatus, making it a mitotic poison.
- **Option 2: Mustard Gas and Azides**:
- Both mustard gas and azides are known to disrupt mitosis and are classified as mitotic poisons.
- **Option 3: Cyanides**:
- Cyanides can also affect cellular processes and are considered to have mitotic poison properties.
- **Option 4: All of These**:
- Since options 1, 2, and 3 are all mitotic poisons, this option is correct as it encompasses all the previous options.

3. **Conclusion**:
- Based on the evaluation of each option, the correct answer is **Option 4: All of These**.

### Final Answer:
The correct answer is **Option 4: All of These**.

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