Mitochondria are site of respiration first reported by Kingsbury and supported by Hogeboom. Mitochondria are related with the oxidation of :

Options

A. Carbohydrates
B. Fats
C. Proteins
D. All the above

Answer

### Step-by-Step Solution:

1. **Understanding Mitochondria**: Mitochondria are known as the "powerhouses of the cell" because they are the primary sites for cellular respiration, where energy (ATP) is produced.

2. **Role of Mitochondria in Respiration**: Mitochondria facilitate the oxidation of various substrates to produce ATP. This process involves breaking down carbohydrates, fats, and proteins.

3. **Analyzing the Options**:
- **Option 1: Carbohydrates**: Carbohydrates are indeed oxidized in mitochondria during aerobic respiration to produce energy.
- **Option 2: Fats**: Fats can also be oxidized in mitochondria, especially when carbohydrates are in short supply.
- **Option 3: Proteins**: Proteins can be used as a source of energy through oxidation in mitochondria, although this is less common than carbohydrates and fats.
- **Option 4: All of the above**: This option encompasses carbohydrates, fats, and proteins, indicating that all these macromolecules can be oxidized in mitochondria.

4. **Conclusion**: Since all three substrates (carbohydrates, fats, and proteins) are oxidized in mitochondria, the correct answer is **Option 4: All of the above**.

### Final Answer:
Mitochondria are related with the oxidation of **all of the above** (carbohydrates, fats, and proteins).

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