Following are the principle action of insulin except :-

Options

A. Increase transport of Glucose in to the cells
B. Stimulate glycogenesis
C. Promote Glycogenolysis
D. Increase lipogenesis

Answer

To answer the question "Following are the principal actions of insulin except:", we need to evaluate the options provided and determine which one does not represent a principal action of insulin.

### Step-by-Step Solution:

1. **Understand the Role of Insulin**: Insulin is a hormone produced by the pancreas that plays a crucial role in regulating glucose levels in the blood and facilitating the uptake of glucose into cells.

2. **Evaluate Each Option**:
- **Option 1: Increase transport of glucose into the cell**: This is a principal action of insulin. Insulin binds to receptors on the cell membrane, facilitating the uptake of glucose into the cells, especially in muscle and fat tissues.

- **Option 2: Stimulate Glycogenesis**: This is also a principal action of insulin. Insulin promotes the conversion of glucose to glycogen (glycogenesis) in the liver and muscle cells, which helps lower blood glucose levels.

- **Option 3: Promote Glycogenolysis**: This option is incorrect as a principal action of insulin. In fact, insulin inhibits glycogenolysis, which is the breakdown of glycogen into glucose. Therefore, this is the action that does not align with the principal actions of insulin.

- **Option 4: Increase lipogenesis**: This is a correct action of insulin. Insulin promotes lipogenesis, which is the synthesis of fatty acids and triglycerides, facilitating fat storage in adipose tissue.

3. **Conclusion**: The only option that does not represent a principal action of insulin is **Option 3: Promote Glycogenolysis**.

### Final Answer:
The correct answer is **Option 3: Promote Glycogenolysis**.

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