Steroid hormones transmit their information by :

Options

A. Stimulating the receptors present on cell membrane.
B. Entering into the cell and modifying cellular contents.
C. Entering into the cell and modifying nuclear organisation.
D. The help of an intracellular second messenger

Answer

To solve the question "Steroid hormones transmit their information by:", we will analyze the options provided and identify the correct mechanism by which steroid hormones function.

### Step-by-Step Solution:

1. **Understanding Steroid Hormones**:
- Steroid hormones are lipid-soluble molecules derived from cholesterol. They can easily pass through cell membranes due to their hydrophobic nature.

**Hint**: Recall that steroid hormones are derived from cholesterol and are lipid-soluble.

2. **Examining the First Option**:
- The first option states that steroid hormones stimulate receptors present on the cell membrane.
- This is incorrect because steroid hormones do not primarily act on membrane-bound receptors; they penetrate the cell membrane instead.

**Hint**: Think about the nature of steroid hormones and their ability to cross cell membranes.

3. **Examining the Second Option**:
- The second option suggests that steroid hormones enter the cell and modify cellular content.
- While steroid hormones do enter the cell, their primary action is not to modify cellular content directly but to interact with specific receptors.

**Hint**: Consider what happens after the hormone enters the cell.

4. **Examining the Third Option**:
- The third option states that steroid hormones enter the cell and modify nuclear organization.
- This is correct. Steroid hormones bind to receptors in the cytoplasm or nucleus and then influence gene expression by interacting with DNA, thus modifying nuclear organization.

**Hint**: Focus on the role of steroid hormones in gene expression and nuclear function.

5. **Examining the Fourth Option**:
- The fourth option mentions the help of an intracellular second messenger.
- This is incorrect for steroid hormones, as they do not rely on second messengers like peptide hormones do.

**Hint**: Recall the difference between steroid hormones and peptide hormones in terms of signaling pathways.

### Conclusion:
The correct answer is that steroid hormones transmit their information by **entering into the cell and modifying nuclear organization** (Option 3).