Hyper secretion of STH leads to :

Options

A. Dwarf & Acromegaly
B. Goitre , Sterility
C. Cretinism, Myxoedema
D. Gigantism & Acromegaly

Answer

**Step-by-Step Solution:**

1. **Understanding Hypersecretion of STH**:
- STH stands for Somatotropin, which is also known as Growth Hormone (GH). Hypersecretion refers to the excessive production of this hormone by the pituitary gland.

2. **Identifying the Effects of Hypersecretion**:
- When there is an overproduction of somatotropin, it can lead to abnormal growth patterns.

3. **Analyzing the Options**:
- **Option 1: Dwarf and Hygromachy**: This option is incorrect. Dwarfism is caused by hyposecretion (underproduction) of somatotropin, not hypersecretion.
- **Option 2: Myxedema and Cretinism**: This option is also incorrect. These conditions are related to thyroid hormone deficiencies, not somatotropin levels.
- **Option 3: Gigantism and Acromegaly**: This option is correct. Gigantism occurs in children and adolescents when there is excessive growth hormone before the growth plates close. Acromegaly occurs in adults when there is excessive growth hormone, leading to the enlargement of bones and tissues.
- **Option 4: Cratinism and Myxedema**: This option is incorrect as it pertains to thyroid hormone issues, not somatotropin.

4. **Conclusion**:
- The correct answer is **Option 4: Gigantism and Acromegaly**. These conditions are the result of hypersecretion of somatotropin.