In absence of ADH, the disease caused is

Options

A. Diabetes mellitus
B. Diabetes insipidus
C. Oligouria
D. Acromegaly

Answer

To answer the question regarding the disease caused in the absence of ADH (Antidiuretic Hormone), we can follow these steps:

### Step-by-Step Solution:

1. **Understand the Role of ADH**:
- ADH, also known as vasopressin, is a hormone produced by the hypothalamus and released from the posterior pituitary gland. Its primary function is to regulate water balance in the body by promoting water reabsorption in the kidneys.

2. **Identify the Consequences of ADH Absence**:
- In the absence of ADH, the kidneys are unable to reabsorb water effectively. This leads to increased urine output and a higher risk of dehydration.

3. **Explore the Options Given**:
- The question provides four options:
- A) Diabetes mellitus
- B) Diabetes insipidus
- C) Oliguria
- D) Acromegaly

4. **Analyze Each Option**:
- **Diabetes mellitus**: This condition is related to insulin deficiency and is not caused by a lack of ADH.
- **Diabetes insipidus**: This condition is directly associated with insufficient ADH, leading to excessive urination and thirst. It is characterized by the inability of the kidneys to concentrate urine due to the lack of ADH.
- **Oliguria**: This refers to low urine output, which is not specifically related to ADH deficiency.
- **Acromegaly**: This condition results from excess growth hormone and is unrelated to ADH.

5. **Select the Correct Answer**:
- Based on the analysis, the correct answer is **Diabetes insipidus**. This condition arises specifically due to the absence or insufficient levels of ADH.

### Final Answer:
In the absence of ADH, the disease caused is **Diabetes insipidus**.