Cretinism is due to abnormal secretion of :

Options

A. Thyroid stimulating hormone
B. Thyroxine
C. Calcitonin
D. Parathormone

Answer

**Step-by-Step Solution:**

1. **Understanding Cretinism**: Cretinism is a condition that arises due to a deficiency in thyroid hormones during early development, particularly in infancy or fetal development. It is characterized by stunted physical and mental growth.

2. **Identifying the Hormones**: The hormones associated with the thyroid gland include:
- Thyroxine (T4)
- Triiodothyronine (T3)
- Calcitonin (which regulates calcium levels)
- Thyroid Stimulating Hormone (TSH) (produced by the pituitary gland)
- Parathyroid Hormone (which also regulates calcium levels)

3. **Determining the Cause of Cretinism**: Cretinism is primarily caused by an abnormal secretion of thyroid hormones, specifically thyroxine (T4). A deficiency in these hormones leads to the symptoms associated with the condition.

4. **Conclusion**: Therefore, the abnormal secretion responsible for Cretinism is primarily due to a lack of thyroxine (T4) from the thyroid gland.

**Final Answer**: Cretinism is due to abnormal secretion of **thyroxine**.

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