Hyposecretion of aldosterone causes :

Options

A. Gull's disease
B. Grave's disease
C. Cushing's disease
D. Addison's disease

Answer

### Step-by-Step Solution:

1. **Understanding Aldosterone**:
- Aldosterone is a hormone produced by the adrenal cortex, which is part of the adrenal glands located on top of the kidneys.
- Its primary function is to regulate sodium and potassium levels in the body, promoting sodium reabsorption and potassium excretion in the kidneys.

2. **Defining Hyposecretion**:
- Hyposecretion refers to the underproduction of a hormone. In this case, it means that the adrenal glands are producing insufficient amounts of aldosterone.

3. **Effects of Aldosterone Hyposecretion**:
- When aldosterone levels are low, the body cannot reabsorb sodium effectively. This leads to decreased sodium levels in the blood, which in turn causes a decrease in water reabsorption.
- The result is lower blood volume and blood pressure, which can lead to various symptoms such as fatigue, weakness, and dehydration.

4. **Identifying Related Disorders**:
- The question provides several disorders: Graves' disease, Cushing's syndrome, and Addison's disease.
- **Graves' disease**: This is related to the thyroid gland and involves hypersecretion of thyroid hormones, not aldosterone.
- **Cushing's syndrome**: This condition is characterized by excess cortisol production, not related to aldosterone levels.
- **Addison's disease**: This is a disorder caused by the hyposecretion of adrenal hormones, including aldosterone.

5. **Conclusion**:
- The correct answer to the question is **Addison's disease**, which is directly associated with the hyposecretion of aldosterone.