Which of the following pair is not effected by secretion of hormone?

Options

A. Rickets and mongolism
B. Diabetes mellitus and cretinism
C. Gigantism and exophthalmia
D. Cretinism and diabetes

Answer

To determine which pair is not affected by the secretion of hormones, we need to analyze each option given in the question.

1. **Ricketts and Mongolism**:
- Ricketts is caused by a deficiency of Vitamin D, which is not a hormone but a vitamin.
- Mongolism (or Down syndrome) is a genetic disorder caused by an extra copy of chromosome 21 (Trisomy 21). This is also not influenced by hormone secretion.
- Therefore, this pair is not affected by hormone secretion.

2. **Diabetes Mellitus and Creatinism**:
- Diabetes Mellitus is caused by insufficient insulin secretion from the pancreas, which is a hormone.
- Creatinism (or Cretinism) is caused by a deficiency of thyroid hormones, specifically in cases of hypothyroidism.
- Both conditions are influenced by hormone secretion, so this pair is affected.

3. **Zygotism and Exophthalmia**:
- Zygotism is not a commonly recognized term in medical literature, but if we assume it refers to a condition related to growth, it could involve growth hormone.
- Exophthalmia (or Graves' disease) is caused by overproduction of thyroid hormones.
- Both conditions are influenced by hormone secretion, so this pair is affected.

4. **Creatinism and Diabetes**:
- As mentioned earlier, Creatinism is related to thyroid hormone deficiency, and Diabetes is related to insulin hormone deficiency.
- Both conditions are influenced by hormone secretion, so this pair is affected.

**Conclusion**: The pair that is not affected by the secretion of hormones is **Option 1: Ricketts and Mongolism**.