Which hormone causes Gluconeogenesis ?

Options

A. Adrenalin
B. Glucagon
C. Insulin
D. Adrenalin + Glucagon

Answer

**Step-by-Step Solution:**

1. **Understanding Gluconeogenesis**:
- Gluconeogenesis is the metabolic process through which organisms synthesize glucose from non-carbohydrate precursors. This process is crucial for maintaining blood glucose levels, especially during fasting or intense exercise.

2. **Identifying Hormones Involved**:
- Several hormones regulate gluconeogenesis. The primary hormones that stimulate this process include glucagon and cortisol (a type of glucocorticoid).

3. **Analyzing the Options**:
- **Option 1: Adrenaline** - Adrenaline (epinephrine) does increase blood glucose levels, but it primarily promotes glycogenolysis (the breakdown of glycogen to glucose) rather than gluconeogenesis directly.
- **Option 2: Glucocorticoids** - Glucocorticoids, such as cortisol, are known to stimulate gluconeogenesis, especially during stress responses.
- **Option 3: Insulin** - Insulin is an anabolic hormone that promotes glucose uptake and storage, thus inhibiting gluconeogenesis.
- **Option 4: Adrenaline + Glucagon** - This option includes both adrenaline and glucagon. While adrenaline has a role in increasing glucose availability, glucagon directly stimulates gluconeogenesis.

4. **Conclusion**:
- The hormone that primarily causes gluconeogenesis is glucagon. However, since the last option includes both adrenaline and glucagon, it can be considered correct in the context of the question.

**Final Answer**: The hormone that causes gluconeogenesis is glucagon, and the best option from the provided choices is "Adrenaline + Glucagon."

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