Fill in the blanks:
1. ATP synthase consists of two major components, `F_(o)" and "F_(1)`. The .... a... headpiece is peripheral membrane protein complex and contains the site for synthesis of ATP from ADP and inorganic phosphate.
2. ... b... is an integral membrane protein complex that forms the channel through which proton crosses the membrane.
3. For each ATP produced, .... c .... passes through .... b.... from the .... d.... to the .... e.... down the electrochemical proton gradient.

Options

A. `a-F_(0) , b-F_(1), c-3H^(+)`, d-matrix, c-inner membrane
B. `a-F_(1) , b-F_(0), c-2H^(+)`, d-intermembrane space, e-matrix
C. `a-F_(0), b-F_(1), c-2H^(+)`, d-intermembrane space, e-matrix
D. `a-F_(1), b-F_(0),c-2H^(+)`, d-matrix,e-intermembrane space

Explanation

To fill in the blanks for the given statements, we can follow these steps:

1. **Identify the components of ATP synthase**:
- ATP synthase consists of two major components, F0 and F1.
- The F1 headpiece is a peripheral membrane protein complex that contains the site for synthesis of ATP from ADP and inorganic phosphate.

**Fill in the blank (a)**: F1

2. **Determine the role of F0**:
- The F0 component is an integral membrane protein complex that forms the channel through which protons cross the membrane.

**Fill in the blank (b)**: F0

3. **Understand the process of ATP production**:
- For each ATP produced, hydrogen ions (protons) pass through the F0 component from the intermembrane space to the matrix down the electrochemical proton gradient.

**Fill in the blank (c)**: Hydrogen ion
**Fill in the blank (d)**: Intermembrane space
**Fill in the blank (e)**: Matrix

Now, let's summarize the filled blanks:

1. **a**: F1
2. **b**: F0
3. **c**: Hydrogen ion
4. **d**: Intermembrane space
5. **e**: Matrix