Mark the incorrect statement regariding landmark events in biotechnology:

Options

A. Eli Lilly an American company prepard Humlin in 1983
B. The first clinical gene therapy was given in 1990 to a four year old girl with adenosine deaminase deficiency
C. Introduction of human alpha-lactalabumin gene was done in a cow Rosie In 1997
D. An American company got patents right on Basmati rice through US patent and Trandemark office in 1987

Answer

To determine the incorrect statement regarding landmark events in biotechnology, we will analyze each of the provided options step by step.

### Step 1: Analyze Option A
- **Statement**: "Eli Lilly and Company prepared Humulin in 1983."
- **Explanation**: Humulin is indeed a form of human insulin produced using recombinant DNA technology by Eli Lilly in 1982, which was commercially available in 1983. However, while it was a significant advancement in biotechnology, the statement claims it was not a landmark event, which is incorrect. Humulin was a landmark event as it was the first genetically engineered drug approved for human use.

### Step 2: Analyze Option B
- **Statement**: "The first clinical gene therapy was given in 1990 to a four-year-old child with ADA deficiency."
- **Explanation**: This statement is accurate. The first successful gene therapy was indeed performed on a child with adenosine deaminase (ADA) deficiency in 1990. This event is considered a landmark in the field of gene therapy.

### Step 3: Analyze Option C
- **Statement**: "Introduction of Human Alpha Lactalbumin gene was done in a cow named Rosie in 1997."
- **Explanation**: This statement is also correct. In 1997, a cow named Rosie was genetically engineered to produce human alpha-lactalbumin, which was a significant achievement in biotechnology, particularly in the area of transgenic animals.

### Step 4: Analyze Option D
- **Statement**: "An American company got patent rights for 'Golden Rice' through the US Patent and Trademark Office."
- **Explanation**: This statement is true. The development of Golden Rice, which is genetically modified to produce beta-carotene, was a landmark event in biotechnology aimed at addressing vitamin A deficiency. The patenting of this rice was a significant event in the field.

### Conclusion
After analyzing all the options, we find that:
- **Incorrect Statement**: Option A is the incorrect statement regarding landmark events in biotechnology, as it downplays the significance of Humulin as a landmark event.

### Final Answer
The incorrect statement regarding landmark events in biotechnology is **Option A**.

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