Which of the following are the reason (s) for Rheumatoid arthritis ? Choose the correct option.
(i) The ability to differentiate pathogens or foreign molecules from self cells increases.
(ii) Body attacks self cells.
(iii) More antibodies are produced in the body.
(iv) The ability to differentiate pathogens or foreign molecules from self cells is lost.

Options

A. I and II
B. II and IV
C. III and IV
D. I and III

Answer

B

Explanation

Autoimmunity is an abnormal immune response in which the immune system of the body starts rejecting its own body cells or 'self' cells and molecules. Sometimes, body loose its ability to differentiate between pathogen or foreign molecules from self cell and attacks self-cells. This results in damage to the body.
While if any foreign antigen enters into body the lymphocytes because more active and produces more antibodies in its response in the body.