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Reductive amination does not require:...

Reductive amination does not require:

A

keto acids

B

Ammonium ion

C

Reducing agent

D

Nitrogenase

Text Solution

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The correct Answer is:
**Step-by-Step Solution:** 1. **Understanding Reductive Amination**: Reductive amination is a biochemical process where ammonia reacts with a keto acid to form an amino acid. This process typically involves the conversion of alpha-ketoglutarate to glutamate. 2. **Identifying the Components**: In the reductive amination process, the key components involved are: - A keto acid (e.g., alpha-ketoglutarate) - Ammonium ion (NH4+) - A reducing agent (often NADPH) - An enzyme (in this case, Glutamate Dehydrogenase) 3. **Analyzing the Options**: The question asks which component is not required for reductive amination. The options provided are: - Keto Acids - Ammonium - Iron - Reducing Agent - Nitrogenase 4. **Evaluating Each Option**: - **Keto Acids**: Required for the reaction as they react with ammonium to form amino acids. - **Ammonium**: Essential as it provides the nitrogen needed for amino acid synthesis. - **Iron**: Not directly involved in the reductive amination process. - **Reducing Agent**: Necessary for the reduction of the keto acid. - **Nitrogenase**: This enzyme is involved in nitrogen fixation and is not required for reductive amination. 5. **Conclusion**: The component that is not required for reductive amination is **Iron**. **Final Answer**: Iron ---
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