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In reductive amination, the product is:...

In reductive amination, the product is:

A

`alpha` ketoglutaric acid

B

glutamine

C

glutamate

D

alanine

Text Solution

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The correct Answer is:
**Step-by-Step Solution:** 1. **Understanding Reductive Amination:** - Reductive amination is a biochemical process where an amino group is introduced into a carbonyl compound, typically an alpha-keto acid, in the presence of reducing agents. 2. **Identifying Reactants:** - In this case, the primary reactant is alpha-ketoglutaric acid (α-ketoglutarate), and it reacts with ammonia (NH₃). 3. **Role of Enzymes:** - The enzyme involved in this reaction is Glutamate Dehydrogenase. This enzyme facilitates the conversion of alpha-ketoglutarate and ammonia into glutamate. 4. **Reaction Overview:** - The reaction can be summarized as: \[ \text{α-ketoglutarate} + \text{NH}_3 + \text{NADPH} \xrightarrow{\text{Glutamate Dehydrogenase} } \text{Glutamate} + \text{NADP}^+ + \text{H}_2\text{O} \] 5. **Identifying the Product:** - The primary product of this reaction is glutamate (also known as glutamic acid). 6. **Conclusion:** - Therefore, in reductive amination involving alpha-ketoglutaric acid and ammonia, the product formed is glutamate. **Final Answer:** - The product of reductive amination is **Glutamate (Glutamic Acid)**. ---
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