Person with Klinefelrte's syndrome have chromosomes

Options

A. XX
B. XY
C. XXY
D. XYY

Answer

### Step-by-Step Solution:

1. **Understanding Klinefelter's Syndrome**: Klinefelter's syndrome is a genetic condition that occurs in males when they have an extra X chromosome. This results in a total of 47 chromosomes instead of the typical 46.

2. **Chromosomal Composition**: In Klinefelter's syndrome, the chromosomal makeup is XXY. This means that instead of the normal XY configuration found in typical males, individuals with Klinefelter's syndrome have one additional X chromosome.

3. **Causes of Klinefelter's Syndrome**: The syndrome can arise due to nondisjunction during meiosis, where the chromosomes fail to separate properly. This can happen in either the egg or the sperm, leading to the fertilization of a normal gamete (22 + X or 22 + Y) with an abnormal gamete (22 + XX or 22 + XY).

4. **Physical Characteristics**: Individuals with Klinefelter's syndrome typically exhibit male physical traits but may also show some female characteristics. These can include breast development, higher-pitched voice, and infertility.

5. **Conclusion**: Therefore, the correct answer to the question is that a person with Klinefelter's syndrome has an XXY chromosomal configuration.