Which of the following statement is not correct regarding malarial infection?

Options

A. Plasmodium enters the human body as sporozoites through the bite of freshly moulted female Anopheles mosquito
B. High fever recurring every three to four days
C. Sporozoites initially multiply within the liver cells and then attack the RBCs resulting in their rupture
D. When a female Anopheles mosquito bites an infected person, these parasites enter the mosquito's body and undergo further development

Explanation

To determine which statement is not correct regarding malarial infection, let's analyze the information provided in the video transcript step by step.

### Step-by-Step Solution:

1. **Understanding the Cause of Malaria**:
- Malaria is caused by a protozoan parasite known as *Plasmodium* species. This is a correct statement.

2. **Transmission of Malaria**:
- The disease is transmitted through the bite of a female Anopheles mosquito. This is also a correct statement.

3. **Entry of Parasite into the Human Body**:
- When the female Anopheles mosquito bites a human, it injects sporozoites into the bloodstream. This is accurate.

4. **Invasion of Cells**:
- The sporozoites can invade liver cells (hepatic cells) and red blood cells (RBCs). This statement is correct as well.

5. **Symptoms of Malaria**:
- A common symptom of malaria is high fever that recurs every 3 to 4 days. This is a recognized characteristic of malaria.

6. **Life Cycle of the Parasite**:
- When a female Anopheles mosquito bites an infected person, the parasites do enter the mosquito's body and undergo further development. This is also correct.

### Conclusion:
Based on the analysis of the statements, if one of the options provided in the question contradicts any of these established facts about malaria, that would be the incorrect statement.